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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1951 2
1952 10
1953 10
1954 12
1955 7
1956 2
1957 4
1958 7
1959 3
1960 8
1961 18
1962 16
1963 27
1964 23
1965 17
1966 21
1967 20
1968 24
1969 28
1970 40
1971 34
1972 32
1973 33
1974 29
1975 22
1976 17
1977 18
1978 25
1979 23
1980 28
1981 45
1982 28
1983 23
1984 59
1985 43
1986 40
1987 44
1988 26
1989 36
1990 44
1991 52
1992 50
1993 37
1994 53
1995 46
1996 34
1997 36
1998 38
1999 53
2000 42
2001 42
2002 36
2003 46
2004 48
2005 41
2006 55
2007 65
2008 48
2009 59
2010 68
2011 61
2012 82
2013 102
2014 122
2015 97
2016 112
2017 106
2018 124
2019 125
2020 111
2021 111
2022 108
2023 99
2024 33

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3,151 results

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Page 1
Primaquine derivatives: Modifications of the terminal amino group.
Zorc B, Perković I, Pavić K, Rajić Z, Beus M. Zorc B, et al. Eur J Med Chem. 2019 Nov 15;182:111640. doi: 10.1016/j.ejmech.2019.111640. Epub 2019 Aug 23. Eur J Med Chem. 2019. PMID: 31472472 Free PMC article. Review.
Numerous modifications of the well-known antimalarial drug primaquine, both at the quinoline ring and at the primary amino group, have been reported, mostly to obtain antimalarial agents with improved bioavailability, reduced toxicity and/or prolonged activity. ...The modi …
Numerous modifications of the well-known antimalarial drug primaquine, both at the quinoline ring and at the primary amino group, hav …
Primaquine: the risks and the benefits.
Ashley EA, Recht J, White NJ. Ashley EA, et al. Malar J. 2014 Nov 3;13:418. doi: 10.1186/1475-2875-13-418. Malar J. 2014. PMID: 25363455 Free PMC article. Review.
Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gametocytocide in falciparum malaria. ...In six decades of primaquine use in approximately 200 million people, 14 deaths have been reported …
Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gameto …
Primaquine therapy for malaria.
Baird JK, Hoffman SL. Baird JK, et al. Clin Infect Dis. 2004 Nov 1;39(9):1336-45. doi: 10.1086/424663. Epub 2004 Oct 12. Clin Infect Dis. 2004. PMID: 15494911 Review.
Primaquine is the only available drug for preventing relapse of malaria, and confusion surrounds its use. ...Supervision of therapy profoundly impacts the risk of relapse, and almost all reports of malaria resistant to primaquine are associated with lack of such sup …
Primaquine is the only available drug for preventing relapse of malaria, and confusion surrounds its use. ...Supervision of therapy p …
Primaquine pharmacology in the context of CYP 2D6 pharmacogenomics: Current state of the art.
Marcsisin SR, Reichard G, Pybus BS. Marcsisin SR, et al. Pharmacol Ther. 2016 May;161:1-10. doi: 10.1016/j.pharmthera.2016.03.011. Epub 2016 Mar 22. Pharmacol Ther. 2016. PMID: 27016470 Free article. Review.
Primaquine is the only antimalarial drug available to clinicians for the treatment of relapsing forms of malaria. Primaquine development and usage dates back to the 1940s and has been administered to millions of individuals to treat and eliminate malaria infections. …
Primaquine is the only antimalarial drug available to clinicians for the treatment of relapsing forms of malaria. Primaquine d …
Primaquine in vivax malaria: an update and review on management issues.
Fernando D, Rodrigo C, Rajapakse S. Fernando D, et al. Malar J. 2011 Dec 12;10:351. doi: 10.1186/1475-2875-10-351. Malar J. 2011. PMID: 22152065 Free PMC article. Review.
Primaquine was officially licensed as an anti-malarial drug by the FDA in 1952. It has remained the only FDA licensed drug capable of clearing the intra-hepatic schizonts and hypnozoites of Plasmodium vivax. This update and review focuses on five major aspects of primaq …
Primaquine was officially licensed as an anti-malarial drug by the FDA in 1952. It has remained the only FDA licensed drug capable of …
Primaquine resistance in Plasmodium vivax.
Collins WE, Jeffery GM. Collins WE, et al. Am J Trop Med Hyg. 1996 Sep;55(3):243-9. doi: 10.4269/ajtmh.1996.55.243. Am J Trop Med Hyg. 1996. PMID: 8842108 Review.
Reports have appeared calling attention to what has been termed primaquine resistance in Plasmodium vivax in several geographic areas. ...The occurrence of relapses in P. vivax after primaquine therapy would be assumed to be the most reliable indication of resistanc …
Reports have appeared calling attention to what has been termed primaquine resistance in Plasmodium vivax in several geographic areas …
Primaquine revisited six decades after its discovery.
Vale N, Moreira R, Gomes P. Vale N, et al. Eur J Med Chem. 2009 Mar;44(3):937-53. doi: 10.1016/j.ejmech.2008.08.011. Epub 2008 Sep 11. Eur J Med Chem. 2009. PMID: 18930565 Review.
Primaquine was firstly synthesized in 1946 in the USA, and is the most representative member of the anti-malarial 8-aminoquinolines. ...The present text revisits primaquine and its properties on the occasion of its 60th anniversary and aims to give a general overvie …
Primaquine was firstly synthesized in 1946 in the USA, and is the most representative member of the anti-malarial 8-aminoquinolines. …
Primaquine radical cure of Plasmodium vivax: a critical review of the literature.
John GK, Douglas NM, von Seidlein L, Nosten F, Baird JK, White NJ, Price RN. John GK, et al. Malar J. 2012 Aug 17;11:280. doi: 10.1186/1475-2875-11-280. Malar J. 2012. PMID: 22900786 Free PMC article. Review.
BACKGROUND: Primaquine has been the only widely available hypnozoitocidal anti-malarial drug for half a century. ...There was marked heterogeneity in study design, particularly primaquine dosing and duration of follow up. The median rate of recurrence following very …
BACKGROUND: Primaquine has been the only widely available hypnozoitocidal anti-malarial drug for half a century. ...There was marked …
Therapeutic failure of primaquine and need for new medicines in radical cure of Plasmodium vivax.
Thomas D, Tazerouni H, Sundararaj KG, Cooper JC. Thomas D, et al. Acta Trop. 2016 Aug;160:35-8. doi: 10.1016/j.actatropica.2016.04.009. Epub 2016 Apr 21. Acta Trop. 2016. PMID: 27109040 Review.
Direct evidence of resistance to primaquine by hypnozoites has not yet been shown. There are some reports detailing risk of primaquine resistance in specific regions, but the overall distribution of primaquine resistance in P. vivax-infected people is largely …
Direct evidence of resistance to primaquine by hypnozoites has not yet been shown. There are some reports detailing risk of primaq …
Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters.
Popovici J, Tebben K, Witkowski B, Serre D. Popovici J, et al. Int J Parasitol Drugs Drug Resist. 2021 Apr;15:36-42. doi: 10.1016/j.ijpddr.2020.12.004. Epub 2021 Jan 24. Int J Parasitol Drugs Drug Resist. 2021. PMID: 33529838 Free PMC article.
All drugs used clinically for killing hypnozoites are 8-aminoquinolines and among them, primaquine has been at the forefront of P. vivax case management for decades. We discuss here the possible factors that could lead to the emergence and selection of P. vivax primaqui …
All drugs used clinically for killing hypnozoites are 8-aminoquinolines and among them, primaquine has been at the forefront of P. vi …
3,151 results

Searches related to "primaquine"